News & General Discussion -  Pfizer hid drug benefit from public (434 views) Notify me whenever anyone posts in this discussion.Subscribe
From: Marci (marcinmin) DelphiPlus Member Icon Posted by hostJun-5 10:45 AM 
To: All  (1 of 22) 
June 4 at 7:05 PM

A team of researchers inside Pfizer made a startling find in 2015: The company’s blockbuster rheumatoid arthritis therapy Enbrel, a powerful anti-inflammatory drug, appeared to reduce the risk of Alzheimer’s disease by 64 percent.

The results were from an analysis of hundreds of thousands of insurance claims. Verifying that the drug would actually have that effect in people would require a costly clinical trial — and after several years of internal discussion, Pfizer opted against further investigation and chose not to make the data public, the company confirmed.

Researchers in the company’s division of inflammation and immunology urged Pfizer to conduct a clinical trial on thousands of patients, which they estimated would cost $80 million, to see if the signal contained in the data was real, according to an internal company document obtained by The Washington Post.

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From: Bike (URALTOURIST1) DelphiPlus Member IconJun-5 6:59 PM 
To: Marci (marcinmin) DelphiPlus Member Icon  (2 of 22) 
 117061.2 in reply to 117061.1 

OK, Fine, just as gasoline is an excellent cleaning agent, most petro companies decline to advertise that fact.  Should we mandate that companies MUST disclose all effective uses of any product?

As has been noted, it can cost million$ to liability insure use of products if used in functions not envisaged by the maker.  Same applies to case studies or laboratory use studies for all the unintended uses that pop up.


USCG Engineer 1961-1982

From: Marci (marcinmin) DelphiPlus Member Icon Posted by hostJun-5 7:05 PM 
To: Bike (URALTOURIST1) DelphiPlus Member Icon  (3 of 22) 
 117061.3 in reply to 117061.2 

Yes we wouldn’t want Big pharma to incur any costs? They are barely squeaking by

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From: Black Cat (NYTSHADE) DelphiPlus Member IconJun-5 8:36 PM 
To: Bike (URALTOURIST1) DelphiPlus Member Icon  (4 of 22) 
 117061.4 in reply to 117061.2 

Like Viagra?


From: albatlerJun-6 1:56 PM 
To: Marci (marcinmin) DelphiPlus Member Icon  (5 of 22) 
 117061.5 in reply to 117061.1 

I have a heart condition that makes it erratic..

I take a medicine that does a fine job at 50 mg per day..

it is even more effective ,when I split the pill and take two a day..

should I force the company to spread that news???




From: Black_BeardJun-9 1:11 AM 
To: albatler  (6 of 22) 
 117061.6 in reply to 117061.5 

Does the drug also cure hemorrhoids? Then yes you should force the company to take it in the ass.

Understand the subject first.





From: albatlerJun-9 4:35 AM 
To: Black_Beard  (7 of 22) 
 117061.7 in reply to 117061.6 

understand what subject??



From: Black_BeardJun-9 10:06 PM 
To: albatler  (8 of 22) 
 117061.8 in reply to 117061.7 

The subject was Pfizer patients discovering a drug they were taking also had a bonus affect on something else. Pfizer would not promote the alternative use.

You simply found you could take your daily single dosage, split it in half, and take it twice a day. And you think your drug company should pay you for learning simple mathematics?





From: albatlerJun-10 9:15 AM 
To: Black_Beard  (9 of 22) 
 117061.9 in reply to 117061.8 

nope, the drug company wanted me to take it twice a day..

the doctors claimed once a day was the preferred way..

interesting take, the drug company had been pushing one pill a day for decades..

they came out with a 1/2 strength pill at 5 times the price..

I still buy the cheap pill and split my way thru life..


From: Marci (marcinmin) DelphiPlus Member Icon Posted by hostJun-10 9:37 AM 
To: albatler  (10 of 22) 
 117061.10 in reply to 117061.9 

the point is that your example isn't analogous to a completely different use for the same drug - you are just tweaking the dosage. It doesn't cost the drug company any more or less if you split a pill. The drug manufacturers allow for doctors to increase or decrease dosage or even to tweak it a little by cutting a pill in half and taking it twice as often.

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