Thank you for this additional information about Manicomio.

Last race at Aqueduct yesterday, Genetic Gem bumped horse next to her out of the gate, stumbled and broke her pelvis, it was her first start, how terribly sad. My condolences to her connections. (I did not see this race, just came across this tweet today)

http://mobile.equibase.com/View.cfm/ResultsChart?t=AQU&c=USA&d=2021-11-28&n=10&s=D

Saw this race and she was out of the picture immediately.  Chart notes said something like rear was frozen so I didn't know what occurred with her.  So heartbreaking;  didn't know this was her first race.  May she run in the Lord's meadows now.

She’s A Winner died after a bout of colic, RIP sweet girl, my condolences to her connections

https://www.bloodhorse.com/horse-racing/articles/255273/shes-a-winner-dam-of-bluegrass-cat-euthanized-at-25

What a great producer she was for WinStar.  Wish Paulick Report could have used a photo of her instead of Bluegrass Cat in their announcement of her loss.  Thank you to Bloodhorse for finding an image of this beautiful and great mare.  May she rest in peace.

Aw, she is the dam of my Martino’s sire - Bluegrass Cat.

RIP sweet mama.

Simply Ravishing’s dam has died at 13:( RIP Four Wishes, my condolences to her connections.

https://www.bloodhorse.com/horse-racing/articles/255360/four-wishes-dam-of-simply-ravishing-dies-at-13

OMG! Medina Spirit has died, collapsed after his workout today. RIP MS, my condolences to his connections.

https://www.bloodhorse.com/horse-racing/articles/255412/medina-spirit-collapses-dies-after-santa-anita-workout

So shocked to read this.  Terrible loss of a great horse.  So sudden but at least it was quick and he did not suffer.