It depends on what, or who you want to help.
If you're looking for specific, devestated communities - take your pick.
WIRES (the Wildlife Rescue) is doing well, I actually spoke to a lovely woman there this morning.
RSPCA is always a safe bet, but there are specific animal shelters there.
Otherwise, Red Cross or Salvos are long standing organisations who know what they're doing and can get people what they need.
I'm a sucker for an orphaned joey, so I'm making joey pouches.
I suggest you look to the smaller, independent sanctuaries. They're not getting much attention.