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This site has an active link just about every line, but it bring up good points.
I'd think that the modifications make them less likely to reproduce, so the genetically modified ones will have to be constantly re-introduced to compete with those non-modified.
However, there are always uncertainties as to how the ecosystem will respond. There might be an important niche we are unaware of. However, that conflicts with the need to reduce disease.
But going back a few more steps into evolutionary biology, disease is one of the ways to hold various populations in check and nuisance pests also tend to drive invasive species (even hairless primates) out of the swamps and other areas, or at least keep the numbers from overwhelming the local ecosystems. Of course now with electricity and air conditioning those fetid swamps are no longer natural obstacles to settlement and building of vast cities.
They must have looked at all possible outcomes and think the benefits outweigh the risks.
Since the female offspring fathered by the genetically modified male mosquitoes don't survive, it results in a population crash. It also eliminates the need for pesticides that kills many beneficial insects as collateral damage.
Then it’s positive unless losing mosquitos destroys the ecosystem in a different way.
Yeah. Presently there's no known harm but you never really know.
Speaking of killing a lot of very unwanted insects, there is a video called "Drone vs Bald Faced Hornets". Dude flew a fairly big drone right underneath a big hornet nest. The noise of the spinning propellers made the hornets angry. They all tried to swarm the drone, and they kept hitting the spinning blades and going splat.
The blades were spinning fast enough to sling all the bug juice off and not affect their aerodynamic lift. The angry hornets came wave after wave, trying to sting the drone, which just methodically chopped them up, until after nearly 5 minutes or so, the nest was effectively devoid of hornets. The pilot landed the drone about a hundred yards away and the video ends showing the entire drone just dripping with hornet bits.